Spero Therapeutics Stock Analysis

SPRO Stock  USD 2.56  0.10  3.76%   
Spero Therapeutics is overvalued with Real Value of 1.71 and Target Price of 5.0. The main objective of Spero Therapeutics stock analysis is to determine its intrinsic value, which is an estimate of what Spero Therapeutics is worth, separate from its market price. There are two main types of Spero Therapeutics' stock analysis: fundamental analysis and technical analysis.
The Spero Therapeutics stock is traded in the USA on NASDAQ Exchange, with the market opening at 09:30:00 and closing at 16:00:00 every Mon,Tue,Wed,Thu,Fri except for officially observed holidays in the USA. Spero Therapeutics is usually not traded on Christmas Day, New Year 's Day, National Mourning Day, Dr . Martin Luther King Jr 's Birthday, Washington 's Birthday, Good Friday, Memorial Day, Juneteenth Holiday, Independence Day, Labour Day, Thanksgiving Day. Spero Stock trading window is adjusted to America/New York timezone.
Check out World Market Map to better understand how to build diversified portfolios, which includes a position in Spero Therapeutics. Also, note that the market value of any company could be closely tied with the direction of predictive economic indicators such as signals in metropolitan statistical area.
To learn how to invest in Spero Stock, please use our How to Invest in Spero Therapeutics guide.

Spero Stock Analysis Notes

About 24.0% of the company outstanding shares are owned by corporate insiders. The book value of Spero Therapeutics was at this time reported as 0.61. The company recorded a loss per share of 1.29. Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying, developing, and commercializing treatments for multi-drug resistant bacterial infections and rare diseases in the United States. The company was founded in 2013 and is headquartered in Cambridge, Massachusetts. Spero Therapeutics operates under Biotechnology classification in the United States and is traded on NASDAQ Exchange. It employs 41 people. To find out more about Spero Therapeutics contact the company at (857) 242-1600 or learn more at https://sperotherapeutics.com.

Spero Therapeutics Investment Alerts

Spero Therapeutics is way too risky over 90 days horizon
Spero Therapeutics appears to be risky and price may revert if volatility continues
The company reported the previous year's revenue of 27.4 M. Net Loss for the year was (68.57 M) with loss before overhead, payroll, taxes, and interest of (48.45 M).
Spero Therapeutics currently holds about 45.4 M in cash with (23.44 M) of positive cash flow from operations. This results in cash-per-share (CPS) ratio of 1.29.
Roughly 24.0% of the company outstanding shares are owned by corporate insiders
Latest headline from newsweek.com: Is California pushing for noncitizens to oversee elections What to know

Spero Therapeutics Upcoming and Recent Events

Earnings reports are used by Spero Therapeutics to provide an update of all three financial statements, including the income statement, the balance sheet, and the cash flow statement. Every quarterly earnings report provides investors with three things: an overview of sales, expenses, and net income for the most recent period..
4th of April 2024
Upcoming Quarterly Report
View
9th of May 2024
Next Financial Report
View
31st of December 2023
Next Fiscal Quarter End
View
4th of April 2024
Next Fiscal Year End
View
30th of September 2023
Last Quarter Report
View
31st of December 2022
Last Financial Announcement
View

Spero Largest EPS Surprises

Earnings surprises can significantly impact Spero Therapeutics' stock price both in the short term and over time. Negative earnings surprises usually result in a price decline. However, it has been seen that positive earnings surprises lead to an immediate rise in a stock's price and a gradual increase over time. This is why we often hear news about some companies beating earning projections. Financial analysts spend a large amount of time predicting earnings per share (EPS) along with other important future indicators. Many analysts use forecasting models, management guidance, and additional fundamental information to derive an EPS estimate.
Reported
Fiscal Date
Estimated EPS
Reported EPS
Surprise
2022-11-14
2022-09-30-0.3-0.33-0.0310 
2024-08-05
2024-06-30-0.38-0.330.0513 
2025-03-11
2024-12-31-0.31-0.3669-0.056918 
View All Earnings Estimates

Spero Therapeutics Environmental, Social, and Governance (ESG) Scores

Spero Therapeutics' ESG score is a quantitative measure that evaluates Spero Therapeutics' performance and commitment regarding environmental, social, and governance (ESG) factors. These scores are becoming increasingly crucial in investment decision-making processes, providing insights into non-financial aspects of Spero Therapeutics' operations that may have significant financial implications and affect Spero Therapeutics' stock price as well as guide investors towards more socially responsible investments.

Spero Stock Institutional Investors

Shares
Citadel Advisors Llc2024-12-31
172.9 K
Bridgeway Capital Management, Llc2025-03-31
154.8 K
State Street Corp2025-03-31
148.9 K
Dafna Capital Management Llc2025-03-31
125 K
Squarepoint Ops Llc2025-03-31
92.9 K
Northern Trust Corp2024-12-31
86.4 K
Jpmorgan Chase & Co2025-03-31
60.8 K
Prudential Financial Inc2025-03-31
56 K
Jane Street Group Llc2024-12-31
52.9 K
Anson Funds Management Lp2025-03-31
3.8 M
Pfizer Inc2025-03-31
2.4 M
Note, although Spero Therapeutics' institutional investors appear to be way more sophisticated than retail investors, it remains unclear if professional active investment managers can reliably enhance risk-adjusted returns by an amount that exceeds fees and expenses.

Spero Market Capitalization

The company currently falls under 'Small-Cap' category with a current market capitalization of 148.72 M.

Spero Profitablity

The company has Profit Margin (PM) of (1.56) %, which may suggest that it does not properly executes on its current pricing strategies or is unable to control all of the operational costs. This is way below average. Similarly, it shows Operating Margin (OM) of (2.48) %, which suggests for every $100 dollars of sales, it generated a net operating loss of $2.48.
Last ReportedProjected for Next Year
Return On Tangible Assets(0.62)(0.65)
Return On Capital Employed(1.19)(1.25)
Return On Assets(0.62)(0.65)
Return On Equity(1.49)(1.56)

Management Efficiency

Spero Therapeutics has return on total asset (ROA) of (0.3721) % which means that it has lost $0.3721 on every $100 spent on assets. This is way below average. Similarly, it shows a return on stockholder's equity (ROE) of (1.0728) %, meaning that it created substantial loss on money invested by shareholders. Spero Therapeutics' management efficiency ratios could be used to measure how well Spero Therapeutics manages its routine affairs as well as how well it operates its assets and liabilities. As of the 6th of June 2025, Return On Tangible Assets is likely to drop to -0.65. In addition to that, Return On Capital Employed is likely to drop to -1.25. At this time, Spero Therapeutics' Total Assets are very stable compared to the past year. As of the 6th of June 2025, Debt To Assets is likely to grow to 0.05, while Net Tangible Assets are likely to drop about 70.9 M.
Last ReportedProjected for Next Year
Book Value Per Share 0.85  0.81 
Tangible Book Value Per Share 0.85  0.81 
Enterprise Value Over EBITDA(0.10)(0.10)
Price Book Value Ratio 1.21  1.15 
Enterprise Value Multiple(0.10)(0.10)
Price Fair Value 1.21  1.15 
Enterprise Value7.1 M6.7 M
The strategic initiatives led by Spero Therapeutics' management are central to its market success. By analyzing these initiatives, we provide a clear picture of the stock's growth prospects.
Operating Margin
(2.48)
Profit Margin
(1.56)
Beta
0.228
Return On Assets
(0.37)
Return On Equity
(1.07)

Technical Drivers

As of the 6th of June, Spero Therapeutics has the Semi Deviation of 3.3, coefficient of variation of 806.99, and Risk Adjusted Performance of 0.2174. In relation to fundamental indicators, the technical analysis model makes it possible for you to check existing technical drivers of Spero Therapeutics, as well as the relationship between them.

Spero Therapeutics Price Movement Analysis

Execute Study
The output start index for this execution was thirteen with a total number of output elements of fourty-eight. The Bollinger Bands is very popular indicator that was developed by John Bollinger. It consist of three lines. Spero Therapeutics middle band is a simple moving average of its typical price. The upper and lower bands are (N) standard deviations above and below the middle band. The bands widen and narrow when the volatility of the price is higher or lower, respectively. The upper and lower bands can also be interpreted as price targets for Spero Therapeutics. When the price bounces off of the lower band and crosses the middle band, then the upper band becomes the price target.

Spero Therapeutics Insider Trading Activities

Some recent studies suggest that insider trading raises the cost of capital for securities issuers and decreases overall economic growth. Trading by specific Spero Therapeutics insiders, such as employees or executives, is commonly permitted as long as it does not rely on Spero Therapeutics' material information that is not in the public domain. Local jurisdictions usually require such trading to be reported in order to monitor insider transactions. In many U.S. states, trading conducted by corporate officers, key employees, directors, or significant shareholders must be reported to the regulator or publicly disclosed, usually within a few business days of the trade. In these cases Spero Therapeutics insiders are required to file a Form 4 with the U.S. Securities and Exchange Commission (SEC) when buying or selling shares of their own companies.
 
Esther Rajavelu over a month ago
Acquisition by Esther Rajavelu of 185000 shares of Spero Therapeutics subject to Rule 16b-3
 
Timothy Keutzer over two months ago
Acquisition by Timothy Keutzer of 2661 shares of Spero Therapeutics subject to Rule 16b-3
 
Mahadevia Ankit over three months ago
Disposition of 55260 shares by Mahadevia Ankit of Spero Therapeutics at 0.78 subject to Rule 16b-3
 
Shukla Sath over three months ago
Acquisition by Shukla Sath of 751407 shares of Spero Therapeutics subject to Rule 16b-3
 
Aquilo Capital Management, Llc over three months ago
Acquisition by Aquilo Capital Management, Llc of 16885 shares of Spero Therapeutics at 8.7884 subject to Rule 16b-3
 
Aquilo Capital, L.p. over six months ago
Acquisition by Aquilo Capital, L.p. of 727 shares of Spero Therapeutics at 5.235 subject to Rule 16b-3
 
Esther Rajavelu over six months ago
Disposition of 17245 shares by Esther Rajavelu of Spero Therapeutics at 1.3 subject to Rule 16b-3
 
Tregoning Kathleen over six months ago
Acquisition by Tregoning Kathleen of 35604 shares of Spero Therapeutics at 1.52 subject to Rule 16b-3
 
Gsk Plc over six months ago
Discretionary transaction by Gsk Plc of tradable shares of Spero Therapeutics subject to Rule 16b-3
 
Esther Rajavelu over six months ago
Acquisition by Esther Rajavelu of 300000 shares of Spero Therapeutics subject to Rule 16b-3
 
Shukla Sath over six months ago
Disposition of 2757 shares by Shukla Sath of Spero Therapeutics at 1.35 subject to Rule 16b-3
 
Pottage John C Jr over six months ago
Acquisition by Pottage John C Jr of 20000 shares of Spero Therapeutics subject to Rule 16b-3

Spero Therapeutics Outstanding Bonds

Spero Therapeutics issues bonds to finance its operations. Corporate bonds make up one of the largest components of the U.S. bond market, which is considered the world's largest securities market. Spero Therapeutics uses the proceeds from bond sales for a wide variety of purposes, including financing ongoing mergers and acquisitions, buying new equipment, investing in research and development, buying back their own stock, paying dividends to shareholders, and even refinancing existing debt. Most Spero bonds can be classified according to their maturity, which is the date when Spero Therapeutics has to pay back the principal to investors. Maturities can be short-term, medium-term, or long-term (more than ten years). Longer-term bonds usually offer higher interest rates but may entail additional risks.

Spero Therapeutics Predictive Daily Indicators

Spero Therapeutics intraday indicators are useful technical analysis tools used by many experienced traders. Just like the conventional technical analysis, daily indicators help intraday investors to analyze the price movement with the timing of Spero Therapeutics stock daily movement. By combining multiple daily indicators into a single trading strategy, you can limit your risk while still earning strong returns on your managed positions.

Spero Therapeutics Corporate Filings

8K
28th of May 2025
Report filed with the SEC to announce major events that shareholders should know about
ViewVerify
10Q
13th of May 2025
Quarterly performance report mandated by Securities and Exchange Commission (SEC), to be filed by publicly traded corporations
ViewVerify
F4
6th of May 2025
The report filed by a party regarding the acquisition or disposition of a company's common stock, as well as derivative securities such as options, warrants, and convertible securities
ViewVerify
8K
28th of April 2025
Report filed with the SEC to announce major events that shareholders should know about
ViewVerify
28th of March 2025
Other Reports
ViewVerify
10K
27th of March 2025
Annual report required by the U.S. Securities and Exchange Commission (SEC) of a company financial performance
ViewVerify
8K
28th of February 2025
Report filed with the SEC to announce major events that shareholders should know about
ViewVerify
F4
5th of February 2025
The report filed by a party regarding the acquisition or disposition of a company's common stock, as well as derivative securities such as options, warrants, and convertible securities
ViewVerify

Spero Therapeutics Forecast Models

Spero Therapeutics' time-series forecasting models are one of many Spero Therapeutics' stock analysis techniques aimed at predicting future share value based on previously observed values. Time-series forecasting models ae widely used for non-stationary data. Non-stationary data are called the data whose statistical properties e.g. the mean and standard deviation are not constant over time but instead, these metrics vary over time. These non-stationary Spero Therapeutics' historical data is usually called time-series. Some empirical experimentation suggests that the statistical forecasting models outperform the models based exclusively on fundamental analysis to predict the direction of the market movement and maximize returns from investment trading.

About Spero Stock Analysis

Stock analysis is the technique used by a trader or investor to examine and evaluate how Spero Therapeutics prices is reacting to, or reflecting on a current market direction and economic conditions. It can be used to make informed decisions about market timing, and when buying or selling Spero shares will generate the highest return on investment. We also built our stock analysis module to help investors to gain an insight into the world economy as a whole, the stock market, thematic ideas. a specific sector, or an individual Stock such as Spero Therapeutics. By using and applying Spero Stock analysis, traders can create a robust methodology for identifying Spero entry and exit points for their positions.
Last ReportedProjected for Next Year
Pretax Profit Margin(2.50)(2.63)
Operating Profit Margin(2.68)(2.81)
Net Loss(2.50)(2.63)
Gross Profit Margin 1.00  1.05 

Current Spero Analysis - Recommendations

We track the performance of the top 100 financial experts across various large and mid-size financial boutiques. Spero analyst recommendations are determined by taking all analyst recommendations and averaging them as Strong Buy, Buy, Hold, Strong Sell or Sell. There is no one specific way to measure analysis performance other than comparing it to the past results via a very sophisticated attribution analysis. Spero analyst consensus and target price projections should be used in combination with other traditional techniques such as stock price forecasting, technical analysis, earnings estimate, and various momentum models.
Target PriceAdvice# of Analysts
5.0Buy3Odds
Spero Therapeutics current and past analyst recommendations published by a number of research institutions as well as average analyst consensus.
Most Spero analysts issue ratings four times a year, at intervals of three months. Ratings are usually accompanied by a target price to helps potential investors understand Spero stock's fair price compared to its market value. Analysts arrive at stock ratings after researching public financial statements of Spero Therapeutics, talking to its executives and customers, or listening to Spero conference calls.
Spero Analyst Advice Details

Spero Stock Analysis Indicators

Spero Therapeutics stock analysis indicators help investors evaluate how Spero Therapeutics stock reacts to ongoing and evolving market conditions. The investors can use it to make informed decisions about market timing and determine when trading Spero Therapeutics shares will generate the highest return on investment. By understating and applying Spero Therapeutics stock analysis, traders can identify Spero Therapeutics position entry and exit signals to maximize returns.
Begin Period Cash Flow76.3 M
Common Stock Shares Outstanding54 M
Total Stockholder Equity46.1 M
Quarterly Earnings Growth Y O Y0.753
Property Plant And Equipment Net3.1 M
Cash And Short Term Investments52.9 M
Cash52.9 M
Accounts Payable7.3 M
Net Debt-48.6 M
50 Day M A0.8993
Total Current Liabilities49.1 M
Other Operating Expenses100.8 M
Non Current Assets Total3.3 M
Non Currrent Assets Other153 K
Stock Based Compensation7.8 M
When determining whether Spero Therapeutics offers a strong return on investment in its stock, a comprehensive analysis is essential. The process typically begins with a thorough review of Spero Therapeutics' financial statements, including income statements, balance sheets, and cash flow statements, to assess its financial health. Key financial ratios are used to gauge profitability, efficiency, and growth potential of Spero Therapeutics Stock. Outlined below are crucial reports that will aid in making a well-informed decision on Spero Therapeutics Stock:
Check out World Market Map to better understand how to build diversified portfolios, which includes a position in Spero Therapeutics. Also, note that the market value of any company could be closely tied with the direction of predictive economic indicators such as signals in metropolitan statistical area.
To learn how to invest in Spero Stock, please use our How to Invest in Spero Therapeutics guide.
You can also try the Theme Ratings module to determine theme ratings based on digital equity recommendations. Macroaxis theme ratings are based on combination of fundamental analysis and risk-adjusted market performance.
Is Biotechnology space expected to grow? Or is there an opportunity to expand the business' product line in the future? Factors like these will boost the valuation of Spero Therapeutics. If investors know Spero will grow in the future, the company's valuation will be higher. The financial industry is built on trying to define current growth potential and future valuation accurately. All the valuation information about Spero Therapeutics listed above have to be considered, but the key to understanding future value is determining which factors weigh more heavily than others.
Quarterly Earnings Growth
0.753
Earnings Share
(1.29)
Revenue Per Share
0.818
Quarterly Revenue Growth
(0.37)
Return On Assets
(0.37)
The market value of Spero Therapeutics is measured differently than its book value, which is the value of Spero that is recorded on the company's balance sheet. Investors also form their own opinion of Spero Therapeutics' value that differs from its market value or its book value, called intrinsic value, which is Spero Therapeutics' true underlying value. Investors use various methods to calculate intrinsic value and buy a stock when its market value falls below its intrinsic value. Because Spero Therapeutics' market value can be influenced by many factors that don't directly affect Spero Therapeutics' underlying business (such as a pandemic or basic market pessimism), market value can vary widely from intrinsic value.
Please note, there is a significant difference between Spero Therapeutics' value and its price as these two are different measures arrived at by different means. Investors typically determine if Spero Therapeutics is a good investment by looking at such factors as earnings, sales, fundamental and technical indicators, competition as well as analyst projections. However, Spero Therapeutics' price is the amount at which it trades on the open market and represents the number that a seller and buyer find agreeable to each party.